Figure 1: Comparative effects of gabapentin, pregabalin, baclofen and the combinations on the discrimination index. Gabapentin (30 mg/kg), pregabalin (30 mg/kg), baclofen (3 mg/kg), gabapentin/baclofen (30/3 mg/kg) and pregabalin/baclofen (30/3 mg/kg) were administered i.p. for 21 consecutive days, from 8-10 A.M every day. Animal performance was evaluated 24 h after the last injection. Data are expressed as means ± SEM. *P < 0.05 and ***P < 0.001 vs control group, #P < 0.05 gabapentin vs pregabalin group. ##P < 0.01 gabapentin vs gabapentin/baclofen.