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  Indian J Med Microbiol
 

Figure 2: Microscopic presentation of colon in TNBS-induced colitis in rats (hematoxylin and eosin staining; original magnification 10×). (A) Normal group, mucus layer and crypts are normal; (B) TNBS-control group, epithelial distortion, crypt damage, and inflammatory cell infiltrates; (C and D) dexamethasone and alosetron groups respectively, moderate mucosal and submucosal inflammation and mucosal inflammatory cell infiltrates; and (E and F), mCPBG and mCPBG + alosetrone, respectively, infiltration of neutrophils and destruction of mucosal architecture. TNBS, 2, 4, 6-trinitrobenzenesulfonic acid; mCPG, meta-chlorophenylbiguanide.

Figure 2: Microscopic presentation of colon in TNBS-induced colitis in rats (hematoxylin and eosin staining; original magnification 10×). (A) Normal group, mucus layer and crypts are normal; (B) TNBS-control group, epithelial distortion, crypt damage, and inflammatory cell infiltrates; (C and D) dexamethasone and alosetron groups respectively, moderate mucosal and submucosal inflammation and mucosal inflammatory cell infiltrates; and (E and F), mCPBG and mCPBG + alosetrone, respectively, infiltration of neutrophils and destruction of mucosal architecture. TNBS, 2, 4, 6-trinitrobenzenesulfonic acid; mCPG, meta-chlorophenylbiguanide.