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  Indian J Med Microbiol
 

Figure 6: Evaluation of cytotoxic effects of IL24-BR2 and IL24 against (a) MCF-7 and (b) HUVEC cells. Significant toxicity was observed when MCF-7 cells treated with IL24 at 20 and 40 µg/mL and IL24-BR2 at 10, 20, and 40 µg/mL. HUVEC cells did not show significant toxicity to IL24-BR2 and IL24, except at 40 µg/mL for both proteins. Data represent the mean + SEM of three independent experiments of triplicates. *P < 0.05, **P < 0.01, and ***P < 0.001 Indicate significant differences compared with negative control group (PBS). ωωP < 0.01, and ωωωP < 0.001 Indicate significant differences between the IL24-BR2 and IL24 alone. IL, Interleukin

Figure 6: Evaluation of cytotoxic effects of IL24-BR2 and IL24 against (a) MCF-7 and (b) HUVEC cells. Significant toxicity was observed when MCF-7 cells treated with IL24 at 20 and 40 µg/mL and IL24-BR2 at 10, 20, and 40 µg/mL. HUVEC cells did not show significant toxicity to IL24-BR2 and IL24, except at 40 µg/mL for both proteins. Data represent the mean + SEM of three independent experiments of triplicates. *<i>P</i> < 0.05, **<i>P</i> < 0.01, and ***<i>P</i> < 0.001 Indicate significant differences compared with negative control group (PBS). ωω<i>P</i> < 0.01, and ωωω<i>P</i> < 0.001 Indicate significant differences between the IL24-BR2 and IL24 alone. IL, Interleukin