Figure 3: Effect of methamphetamine and TQ on SOD enzyme activity in the striatum region. Mice received intraperitoneal methamphetamine (10 mg/kg) four times a day in 2-h intervals and TQ at 5, 10, and 20 mg/kg, 30 min before each methamphetamine injection. The results are presented as mean ± SEM, n = 3. ***P < 0.001 Indicates significant differences compared to the control group; and #P < 0.05 and ###P < 0.001 against the vehicle + methamphetamine group. TQ, Thymoquinone, SOD, superoxide dismutase.